diff --git a/var/spack/repos/builtin/packages/hdf5/hdf5_1.8_gcc10.patch b/var/spack/repos/builtin/packages/hdf5/hdf5_1.8_gcc10.patch
new file mode 100644
index 0000000000..0de8c33c09
--- /dev/null
+++ b/var/spack/repos/builtin/packages/hdf5/hdf5_1.8_gcc10.patch
@@ -0,0 +1,12 @@
+diff -Naur hdf5.orig/fortran/test/tH5T_F03.f90 hdf5/fortran/test/tH5T_F03.f90
+--- hdf5.orig/fortran/test/tH5T_F03.f90	2021-01-19 13:23:11.298000000 +0100
++++ hdf5/fortran/test/tH5T_F03.f90	2021-01-19 13:19:17.637000000 +0100
+@@ -1541,7 +1541,7 @@
+   INTEGER :: A, B, C, D
+   INTEGER :: Aw, Bw, Cw, Dw
+   INTEGER :: i, j
+-  INTEGER, PARAMETER :: hex =  Z'00000003'
++  INTEGER, PARAMETER :: hex =  INT(Z'00000003')
+   TYPE(C_PTR) :: f_ptr
+   INTEGER :: error     ! Error flag
+   !
diff --git a/var/spack/repos/builtin/packages/hdf5/package.py b/var/spack/repos/builtin/packages/hdf5/package.py
index 01c1428766..59e2f98600 100644
--- a/var/spack/repos/builtin/packages/hdf5/package.py
+++ b/var/spack/repos/builtin/packages/hdf5/package.py
@@ -139,6 +139,11 @@ class Hdf5(AutotoolsPackage):
     patch('h5public-skip-mpicxx.patch', when='@:1.8.21,1.10.0:1.10.5+mpi~cxx',
           sha256='b61e2f058964ad85be6ee5ecea10080bf79e73f83ff88d1fa4b602d00209da9c')
 
+    # Fixes BOZ literal constant error when compiled with GCC 10.
+    # The issue is described here: https://github.com/spack/spack/issues/18625
+    patch('hdf5_1.8_gcc10.patch', when='@:1.8.21',
+          sha256='0e20187cda3980a4fdff410da92358b63de7ebef2df1d7a425371af78e50f666')
+
     # The argument 'buf_size' of the C function 'h5fget_file_image_c' is
     # declared as intent(in) though it is modified by the invocation. As a
     # result, aggressive compilers such as Fujitsu's may do a wrong