diff --git a/var/spack/repos/builtin/packages/py-nanobind/package.py b/var/spack/repos/builtin/packages/py-nanobind/package.py
new file mode 100644
index 0000000000..de2a1c7cc7
--- /dev/null
+++ b/var/spack/repos/builtin/packages/py-nanobind/package.py
@@ -0,0 +1,34 @@
+# Copyright 2013-2023 Lawrence Livermore National Security, LLC and other
+# Spack Project Developers. See the top-level COPYRIGHT file for details.
+#
+# SPDX-License-Identifier: (Apache-2.0 OR MIT)
+
+from spack.package import *
+
+
+class PyNanobind(PythonPackage):
+    """nanobind -- Seamless operability between C++11 and Python.
+
+    nanobind is a small binding library that exposes C++ types in
+    Python and vice versa. It is reminiscent of Boost.Python and pybind11
+    and uses near-identical syntax. In contrast to these existing tools,
+    nanobind is more efficient: bindings compile in a shorter amount of time,
+    produce smaller binaries, and have better runtime performance.
+    """
+
+    homepage = "https://nanobind.readthedocs.io"
+    url = "https://github.com/wjakob/nanobind/archive/refs/tags/v1.2.0.tar.gz"
+    git = "https://github.com/wjakob/nanobind.git"
+
+    maintainers("ma595")
+
+    version("master", branch="master", submodules=True)
+    version("1.4.0", tag="v1.4.0", submodules=True)
+    version("1.2.0", tag="v1.2.0", submodules=True)
+
+    depends_on("python@3.8:", type=("build", "run"))
+    depends_on("py-setuptools@42:", type="build")
+    depends_on("py-scikit-build", type="build")
+
+    depends_on("py-cmake@3.17:", type="build")
+    depends_on("py-ninja", type="build")