diff --git a/var/spack/repos/builtin/packages/cuda/package.py b/var/spack/repos/builtin/packages/cuda/package.py
index 77bf03da37..e624acbaa9 100644
--- a/var/spack/repos/builtin/packages/cuda/package.py
+++ b/var/spack/repos/builtin/packages/cuda/package.py
@@ -582,6 +582,8 @@ def setup_build_environment(self, env):
 
     def setup_dependent_build_environment(self, env, dependent_spec):
         env.set("CUDAHOSTCXX", dependent_spec.package.compiler.cxx)
+        env.set("CUDA_HOME", self.prefix)
+        env.set("NVHPC_CUDA_HOME", self.prefix)
 
     @property
     def cmake_prefix_paths(self):
@@ -593,6 +595,7 @@ def cmake_prefix_paths(self):
 
     def setup_run_environment(self, env):
         env.set("CUDA_HOME", self.prefix)
+        env.set("NVHPC_CUDA_HOME", self.prefix)
 
     def install(self, spec, prefix):
         if os.path.exists("/tmp/cuda-installer.log"):