diff --git a/var/spack/repos/builtin/packages/py-pyem/package.py b/var/spack/repos/builtin/packages/py-pyem/package.py
new file mode 100644
index 0000000000..e8940b9722
--- /dev/null
+++ b/var/spack/repos/builtin/packages/py-pyem/package.py
@@ -0,0 +1,27 @@
+# Copyright 2013-2021 Lawrence Livermore National Security, LLC and other
+# Spack Project Developers. See the top-level COPYRIGHT file for details.
+#
+# SPDX-License-Identifier: (Apache-2.0 OR MIT)
+
+from spack import *
+
+
+class PyPyem(PythonPackage):
+    """Project-level Python virtual environment management tool.
+
+    PyEM manages multiple virtual environments local to projects.
+    It provides shortcuts to create, remove, switch between, and run
+    commands against virtual environments created against
+    various Python interpreters."""
+
+    pypi     = "pyem/pyem-2.1.0.tar.gz"
+
+    version('2.1.0', sha256='5234a20427ab2813a8a0bf1e9112d4d854b1b0502b3e63d17c1b1a3c4be9340e')
+
+    depends_on('python@3.7:', type=('build', 'run'))
+    depends_on('py-setuptools', type='build')
+
+    # distutils does not support entry_points, setuptools needed to install pyem binary
+    def patch(self):
+        filter_file(r'from distutils.core import setup',
+                    'from setuptools import setup', 'setup.py')