diff --git a/var/spack/repos/builtin/packages/orca/package.py b/var/spack/repos/builtin/packages/orca/package.py
index f1ed55c1ba..9195c58da0 100644
--- a/var/spack/repos/builtin/packages/orca/package.py
+++ b/var/spack/repos/builtin/packages/orca/package.py
@@ -49,6 +49,8 @@ class Orca(Package):
     )
 
     depends_on("zstd", when="@:4.2.1", type="build")
+    depends_on("libevent", type="run")
+    depends_on("libpciaccess", type="run")
 
     # Map Orca version with the required OpenMPI version
     openmpi_versions = {
@@ -98,3 +100,6 @@ def setup_run_environment(self, env):
         # In 5.0.3-f.1 an RPATH is set to $ORGIN/../lib
         if not self.spec.satisfies("@5.0.3-f.1"):
             env.prepend_path("LD_LIBRARY_PATH", self.prefix.bin)
+            env.prepend_path("LD_LIBRARY_PATH", self.spec["libevent"].prefix.lib)
+            env.prepend_path("LD_LIBRARY_PATH", self.spec["libpciaccess"].prefix.lib)
+            env.prepend_path("LD_LIBRARY_PATH", self.spec["openmpi"].prefix.lib)